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📚 Atropos Dictionary

Welcome to our internal dictionary for TQL and clinical research methodology.

🔍 How to Use

  • Search: Use the search bar at the top (or press s) to find specific terms instantly.
  • Browse: Use the navigation on the left to explore by category.
  • Visuals: Many definitions include diagrams from our Learning Lab materials.

📚 Categories

💻 TQL Reference

Documentation for Temporal Query Language - our internal query language for analyzing patient timelines.

  • Core Concepts - Variables, Time Intervals, Timeline, Empty, Null
  • Temporal Operations - START, END, FIRST_MENTION, LAST_MENTION, INTERSECT, UNION
  • BEFORE Operations - BEFORE, PRESENCE OF, BETWEEN AND RELATIVE TO
  • Boolean Operations - AND, OR, NOT, EXISTS, IF
  • Aggregations - COUNT, EVAL, MIN, MAX
  • Querying Features - Feature queries, ORIGINAL, Entity Event Level, LINK

📋 Study Design

Concepts for designing observational studies and clinical research.

  • Study Types - Case Series, Cohort Study, Case-Control, RCT
  • Design Concepts - PICO/PICOT, Design Diagrams, New Initiator Active Comparator
  • Population - Inclusion/Exclusion Criteria, Index Date, Run-in Period
  • Outcomes & Covariates - Outcome definitions, Demographics, Comorbidity Scores

🏥 Clinical Coding

Medical coding systems and data standards.

  • Diagnosis Codes - ICD-10, ICD-10-CM, ICD-9
  • Procedure Codes - CPT, HCPCS
  • Medication Codes - RxNorm, RxCUI, ATC
  • Lab Codes - LOINC
  • Data Standards - OMOP CDM, EHR/EMR

📊 Methods

Statistical methods and epidemiological concepts.

  • Bias - Selection Bias, Immortal Time Bias, Confounding
  • Propensity Scores - PSM, High-Dimensional PS, Balance Tables
  • Survival Analysis - Kaplan-Meier, Cox Regression, Hazard Ratios
  • Incidence & Rates - Incidence Rate, IRR, Cumulative Incidence
  • Effect Measures - Odds Ratio, Effect Size, E-Value

🎯 Purpose

This dictionary standardizes terminology to improve efficiency and accuracy in clinical delivery. It bridges the gap between clinical concepts, statistical methods, and TQL.

🛠️ Contributing

This dictionary is a living document. To suggest edits:

  1. Go to the GitHub Repository
  2. Navigate to the docs/ folder
  3. Click the Pencil Icon on any file to suggest an edit